Figure 2.

Effects of hyperleptinemia on fetal biometrics in Sham and RUPP rats. Sham or RUPP procedure plus leptin or vehicle infusion were conducted on GD 14 and measurements collected on GD 19. Average fetal weight (A), total fetal weight (B), number of live fetuses (C), and percent absorbed fetuses (D). Data are presented as scattered-dot plots with mean ± SE. The results from the two-way ANOVA are inset. ANOVA, analysis of variance; GD, gestational day; RUPP, reduced uterine perfusion pressure. Sham + Vehicle (N = 13), Sham + Leptin (N = 10), RUPP + Vehicle (N = 11), and RUPP + Leptin (N = 7).