Figure 3.

Effects of hyperleptinemia on placental biometrics in Sham and RUPP rats. Average placental weight (A), total placental weight (B), and placental sufficiency (C). Sham or RUPP procedure plus leptin or vehicle infusion were conducted on GD 14 and measurements collected on GD 19. Data are presented as scattered-dot plots with mean ± SE. The results from the two-way ANOVA are inset. ANOVA, analysis of variance; GD, gestational day; RUPP, reduced uterine perfusion pressure. Sham + Vehicle (N = 13), Sham + Leptin (N = 10), RUPP + Vehicle (N = 11), and RUPP + Leptin (N = 7).