Table 2.

Physiological and plasma parameter in mice used for the plasma incubation experiment (exposure 2)

		Insulin			VEGF
	Naïve	Air	CAP	P	Air	CAP	P
BW, g	28.1 ± 0.4	27.3 ± 1.2	26.9 ± 0.3	0.719	28.3 ± 0.7	28.5 ± 1.0	0.815
Heart:BW, %		0.48 ± 0.01	0.48 ± 0.01	0.920	0.50 ± 0.01	0.52 ± 0.02	0.139
Lung:BW, %		0.51 ± 0.01	0.49 ± 0.02	0.287	0.52 ± 0.03	0.52 ± 0.01	0.919
Glucose, mg/dL	182 ± 4	184 ± 15	170 ± 9	0.435	189 ± 11	165 ± 10	0.142
Insulin, ng/mL		0.41 ± 0.01	0.41 ± 0.01	0.637	0.42 ± 0.01	0.40 ± 0.01	0.109
HOMA-IR		5.4 ± 0.5	4.9 ± 0.2	0.393	5.6 ± 0.3	4.8 ± 0.3	0.100
HOMA-β, %		36.6 ± 3.9	40.2 ± 3.3	0.516	35.3 ± 3.3	41.4 ± 3.1	0.225
VEGF, pg/mL		15.3 ± 2.8	15.4 ± 3.7	0.978	19.8 ± 2.0	13.14 ± 2.1	0.065

Values are means ± SE, n = 4. Physiological parameters measured in naïve mice (aorta donor) and in mice exposed for 9 days (exposure 2) to air or CAP (plasma donor) for the plasma incubation experiment (see Fig. 1B). BW, body weight; HOMA-IR, fasting blood glucose (mmol/L) × fasting plasma insulin levels (mU/L)/22.5; HOMA-β, 20× fasting plasma insulin levels (mU/L)/fasting blood glucose (mmol/L)–3.5, %; VEGF, vascular growth factor.