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. 2021 Mar 5;320(5):H1749–H1761. doi: 10.1152/ajpheart.00925.2020

Table 4.

EV miRNAs and proteins as biomarkers for cardiovascular diseases

Biomarker (miRNAs/Proteins) EV Source Cardiovascular Pathology Reference
miR-1, miR-133a Serum of humans Myocardial damage, acute coronary syndrome (100)
miR-208a Plasma of humans Coronary artery occlusion (29)
miR-208b, miR-499-5p Plasma of humans Increased risk for heart failure (63)
miR-192, has-miR-194, miR-34a Serum of humans Heart failure following acute myocardial infarction (34)
Apolipoprotein D, C-III; complement C1q, C5; platelet basic protein Plasma of humans Indicator of thrombosis, vascular inflammation, myocardial injury (81)

EV, extracellular vesicle.