Figure 8.

Exercise reduces circumferential wall tension in BAPN-treated mice. CWT in the ascending aorta and descending thoracic aorta was significantly reduced in BAPN-treated mice that underwent forced treadmill exercise. CWT was calculated from measured mean arterial pressures and lumen diameters on micro-CT. *P < 0.05 by two-way ANOVA with Tukey’s multiple comparisons test. n = 4 CONV, 4 EX, 4 BAPN-CONV, 5 BAPN-EX. BAPN, β-aminopropionitrile; BAPN-CONV, conventional cage activity; BAPN-EX, forced treadmill exercise; CWT, circumferential wall tension; micro-CT, microcomputed tomography.