Duplicates removed	107
Excluded during initial screening (e.g. press releases; news reports; not relevant drug/indication; preclinical study; reviews; case reports; not randomized trial)	47
Excluded during writing (e.g. reviews; duplicate data; small patient number; nonrandomized/phase I/II trials)	364
Cited efficacy/tolerability articles	47
Cited articles not efficacy/tolerability	33
Search Strategy: EMBASE, MEDLINE and PubMed from 1946 to present. Clinical trial registries/databases and websites were also searched for relevant data. Key words were nintedanib, Ofev, pulmonary fibrosis, ILD. Records were limited to those in English language. Searches last updated 23 Feb 2021