Table 4.
Multiple Cox proportional hazard model for hypertension (HTN)a development.
| Variable | Model I | Model II | Model III | |||
|---|---|---|---|---|---|---|
| HR | 95% CI | HR | 95% CI | HR | 95% CI | |
| Albumin (g/dL) | 0.599 | 0.484–0.741 | 0.654 | 0.521–0.820 | ||
| rs2894536 | ||||||
| Additive model | 1.164 | 1.022–1.325 | 1.158 | 1.017–1.319 | 1.141 | 1.003–1.299 |
| Dominant model | 1.188 | 1.026–1.376 | 1.185 | 1.024–1.371 | 1.176 | 1.015–1.361 |
| Recessive model | 1.225 | 0.777–1.931 | ||||
| rs10972486 | ||||||
| Additive model | 1.090 | 0.990–1.201 | ||||
| Dominant model | 1.160 | 1.015–1.325 | 1.153 | 1.008–1.317 | 1.152 | 1.009–1.316 |
| Recessive model | 1.047 | 0.854–1.282 | ||||
Model I: adjusted for age, sex, and smoking history.
Model II: adjusted for age, sex, smoking history, systolic BP, diastolic BP, body mass index, waist circumference, hemoglobin, platelet, hemoglobin A1c, alanine aminotransferase, γ-glutamyl transferase, triglyceride, and HDL-cholesterol levels.
Model III: adjusted for age, sex, smoking history, systolic BP, diastolic BP, body mass index, waist circumference, hemoglobin, platelet, albumin, hemoglobin A1c, alanine aminotransferase, γ-glutamyl transferase, triglyceride, and HDL-cholesterol levels.
HR, hazard ratio; CI, confidence interval.
aDefined as BP ≥ 140/90 mmHg and/or antihypertensive drug therapy during the follow-up period.