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. 2021 May 28;11:11290. doi: 10.1038/s41598-021-89775-3

Table 5.

Control function instrument variable estimator of the casual HR for the effect of serum albumin levels on HTN development.

Model Albumin (g/dL)
HRa 95% CIa
Dominant model of LOC107986598 polymorphism at rs2894536
Adjusted for age, sex, and smoking history 0.727 0.632–0.836
Adjusted for age, sex, smoking history, systolic BP, diastolic BP, body mass index, waist circumference, hemoglobin, platelet, hemoglobin A1c, alanine aminotransferase, γ-glutamyl transferase, triglyceride, and HDL-cholesterol level 0.762 0.659–0.882
Dominant model of ATP8B5P polymorphism at rs10972486
Adjusted for age, sex, and smoking history 0.723 0.629–0.831
Adjusted for age, sex, smoking history, systolic BP, diastolic BP, body mass index, waist circumference, hemoglobin, platelet, hemoglobin A1c, alanine aminotransferase, γ-glutamyl transferase, triglyceride, and HDL-cholesterol level 0.759 0.656–0.878

aCalculated using a two-stage residual inclusion method.