Table 2.
Baseline demographic and clinical characteristics of HF population.
| LVAD | DTX | HF | |
|---|---|---|---|
| Age (years) | 52.1 ± 2.7 | 48.2 ± 5.3 | 50.1 ± 4.0 |
| Male, n (%) | 34 (80.9) | 5 (71.4) | 39 (76.1) |
| Ischemic cardiomyopathy, n (%) | 17 (40.4) | N/A | 17 (40.4) |
| Non-ischemic cardiomyopathy, n (%) | 24 (57.1) | N/A | 24 (57.1) |
| NYHA class III, n (%) | 10 (23.8) | 1 (14.2) | 11 (19.0) |
| NYHA class IV, n (%) | 31 (73.8) | 6 (85.7) | 37 (66.2) |
| Duration of heart failure (years) | 6.3 ± 1.2 | N/A | 6.3 ± 1.2 |
| LVEF (%) | 19.9 ± 1.1 | 20.6 ± 4.8 | 20.2 ± 2.9 |
| Left ventricular end-diastolic diameter (cm) | 6.5 ± 0.1 | 6.4 ± 0.5 | 6.4 ± 0.3 |
| HbA1c (%) | 6.2 ± 0.9 | N/A | 6.2 ± 0.8 |
| Brain natriuretic peptide (pg/ml) | 1343.5 ± 169.2 | 1285.1 ± 427.2 | 1314.3 ± 298.2 |
| Creatinine (mg/dl) | 1.33 ± 0.07 | 1.73 ± 0.05 | 1.5 ± 0.6 |
| Sodium (mmol/l) | 134.2 ± 0.7 | 134.5 ± 0.7 | 134.3 ± 0.7 |
| Hemoglobin (g/dl) | 12.7 ± 0.3 | 11.2 ± 1.0 | 11.9 ± 0.6 |
| Systolic arterial pressure (mm Hg) | 103.1 ± 2.4 | 111.1 ± 6.4 | 107.1 ± 4.4 |
| Diastolic arterial pressure (mm Hg) | 64.9 ± 2.4 | 67.8 ± 2.4 | 66.3 ± 2.4 |
| Mean right atrial (mm Hg) | 12.3 ± 1.0 | 8.8 ± 2.0 | 10.5 ± 1.5 |
| Pulmonary capillary wedge pressure (mm Hg) | 25.2 ± 1.5 | 20.0 ± 3.0 | 22.6 ± 2.2 |
| Systolic pulmonary arterial pressure (mm Hg) | 54 ± 2.1 | 37.5 ± 3.2 | 45.8 ± 2.6 |
| Diastolic pulmonary arterial pressure (mm Hg) | 26.7 ± 1.5 | 22.1 ± 1.4 | 24.4 ± 1.4 |
| Pulmonary vascular resistance (Wood units) | 3.8 ± 0.3 | 1.4 ± 0.2 | 2.6 ± 0.3 |
| Cardiac index (l/min/m2) | 1.8 ± 0.07 | 2.1 ± 0.1 | 1.9 ± 0.08 |
Values are shown in n (%) or mean ± standard error when appropriate.
NYHA New York Heart Association, HbA1c hemoglobin A1c.