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. 2021 May 28;11:332. doi: 10.1038/s41398-021-01453-0

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a Ranking regarding efficacy and tolerability are assessed by the surface under the cumulative ranking curve (SUCRA) values. A larger SUCRA denotes a more effective and tolerable treatment strategy. b Each treatment strategy is represented by a node of a different colour. The abscissa represents symptom changes as a measure of efficacy (larger values denote more effective treatment strategies), and the ordinate represents drop-out rate as a measure of tolerability (smaller values denote more tolerable treatment strategies). The error bars represent the 95% credible intervals (CrIs). c The treatment strategies were ordered according to the surface under the cumulative ranking curve (SUCRA) for efficacy. Results are shown as the mean difference for symptom changes (lower triangle) and odds ratio for drop-out rates (upper triangle) estimated from the network meta-analysis comparing every pair of the six treatment strategies. Comparisons among the six treatment strategies should be read from left to right. For efficacy, an MD larger than 0 favours the intervention in the column. For tolerability, an OR <1 favours the intervention in the row. MD mean difference, OR odds ratio, CrI credible interval, LF-DLPFC low-frequency rTMS applied over the dorsolateral prefrontal cortex, HF-DLPFC high-frequency rTMS applied over the dorsolateral prefrontal cortex, LF-SMA low-frequency rTMS applied over the supplementary motor area, LF-OFC low-frequency rTMS applied over the orbitofrontal cortex, HF-ACC/mPFC high-frequency rTMS applied over the anterior cingulate cortex/medial prefrontal cortex.