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. 2021 May 28;11:11311. doi: 10.1038/s41598-021-90859-3

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Motor resilience proteins are related of the annual rate of motor decline prior to death in older adults. Figures show model generated trajectories for motor decline for three average participants with low (10th percentile), average (50th percentile) or high (90th percentile) expression levels for VGF or IGFBP5. A higher level of VGF is associated with slower motor decline and a lower level of IGFBP5 is associated with slower motor decline.