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. 2021 May 28;12(6):552. doi: 10.1038/s41419-021-03837-y

Table 1.

Univariate and multivariate analysis of prognostic factors associated with OS and DFS in 150 HCC patients.

HCC patients (n = 150) Univariate analysis of OS Multivariate analysis of OS Univariate analysis of DFS Multivariate analysis of DFS
HR (log rank) 95% CI P-value HR (log rank) 95% CI P-value HR (log rank) 95% CI P-value HR (log rank) 95% CI P-value
Age (years) ≥55/<55 0.926 0.630–1.362 0.695 1.268 0.791–2.034 0.609
Sex Male/female 0.877 0.556–1.384 0.573 0.795 0.514–1.229 0.555
AFP (ng/ml) ≥7/<7 1.727 1.145–2.605 0.008* 1.477 0.953–2.289 0.081 1.991 1.242–3.192 0.004* 1.303 0.868–1.958 0.202
Staining score of KI67 ≥5%/<5% 1.732 1.164–2.578 0.006* 1.644 1.078–2.507 0.021* 1.760 1.130–2.741 0.032* 1.321 0.896–1.947 0.160
HBV Y/N 1.429 0.876–2.329 0.150 1.768 1.092–2.862 0.143
Tumor size (cm) >3/≤3 1.545 1.018–2.345 0.039* 1.358 0.860–2.144 0.189 2.489 1.528–4.056 0.014* 1.146 0.737–1.782 0.544
Mavi Y/N 4.238 2.391–7.511 <0.001* 1.556 0.565–4.282 0.392 1.519 0.780–2.956 <0.001* 1.558 0.613–3.957 0.351
Mivi Y/N 1.634 1.105–2.418 0.013* 1.412 0.946–2.107 0.091 0.940 0.606–1.459 0.025* 1.487 1.027–2.152 0.036*
Cirrhosis Y/N 0.933 0.633–1.374 0.723 0.999 0.584–1.70- 0.701
BCLC stage 0&A/B&C 3.036 1.865–4.940 <0.001* 2.244 0.924–5.446 0.074 0.984 0.576–1.680 <0.001* 2.487 1.099–5.626 0.029*
Staining score of PNO1 High/low 2.098 1.419–3.103 <0.001* 1.703 1.111–2.609 0.014* 0.535 0.316–0.906 <0.001* 2.421 1.605–3.651 <0.001*

Bold and asterisks are used to emphasize that the value is statistically significant.