Fig. 6. The Theileria methyltransferase TaSETup1.
a Analysis of expression (RT-qPCR) the TaSETup genes in macroschizont or merogony culture conditions (37 or 41 °C, respectively). Results were normalized to TaSETup1 at 37 °C and represent three independent experiments (n = 3). Statistical test Dunnett’s multiple comparison two-sided tests showing changes upon merogony: ns=not statistically significant > 0.6389; *p = 0.0488. b Comparison of TaSETup1 predicted structure (beige) with the crystal structure of the human SMYD3 protein (blue, PDB ID: 6IJL), with zoom window of the active site highlighting TaSETup1 H206 residue (red). c Schematic of the TaSETup1 protein, highlighting the SAM binding regions and the H206 residue (red).