Table 1.

Dosage: Maximum recommended doses [14] in comparison with other commonly used drugs Lidocaine and Bupivacaine

Anaesthetic route of administration	Maximum single dose without vasoconstrictor (mg/kg)	Maximum single dose with vasoconstrictor (mg/kg)	Onset of action (min)	Duration of action in isolation (min) [with vasoconstrictor, if available]
Lidocaine infiltration	3 mg/kg per dose, not to exceed 300 mg per dose,	7 mg/kg per dose—not to exceed 500 mg per dose	1–3 min	1/2–2 h [2 to 4 h with epinephrine]
Bupivacaine infiltration	2.5 mg/kg per dose—not to exceed 175 mg per dose	3 mg/kg per dose—not to exceed 225 mg per dose	2–7 min	2–3 h [3–7 h with epinephrine]
Ropivacaine infiltration	3 mg/kg per dose—not to exceed 225 mg per dose	4 mg/kg per dose—not to exceed 225 mg per dose	3–7 min	3–4 h [5–8 h with epinephrine]