Table 1.

Definitions for ISGA used as primary endpoint in CORE 1 and CORE 2 [2]

(Reprinted from Paller et al. [2], Copyright 2016, with permission from Elsevier)

Score	Grade	Definition
0	Clear	Minor residual hypo/hyperpigmentation; no erythema or induration/papulation; no oozing/crusting
1	Almost clear	Trace faint-pink erythema, with barely perceptible induration/papulation and no oozing/crusting
2	Mild	Faint-pink erythema with mild induration/papulation and no oozing/crusting
3	Moderate	Pink–red erythema with moderate induration/papulation with or without oozing/crusting
4	Severe	Deep- or bright-red erythema with severe induration/papulation and with oozing/crusting

ISGA Investigator’s Static Global Assessment