Truncal acne, despite its prevalence, physical and psychological burden, has largely been neglected in prior clinical trials and guidelines.

Recognizing and addressing this shortcoming may reduce the overall burden of acne.

The potential effectiveness of some topical treatments in truncal acne challenge the role of systemic agents.

High-quality studies in truncal and facial acne are needed to expand the evidence base and inform treatment decisions.

In clinical practice, the evaluation and management of both facial and truncal acne, as well as exploring the overall burden, can address the comprehensive needs of our patients.