| Even though melanoma represents a small percentage of all cutaneous cancers, it is responsible for most deaths from skin cancers |
| The survival rate at 5 years for localized melanoma is 98.3% while for metastatic melanoma (MM) is 16% |
| In the last decade melanoma clinical research has completely changed the scenario of therapeutic approaches for patients with unresectable advanced melanoma |
| Multiple targets for drug development have been identified to treat advanced melanoma and are currently undergoing development |
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