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. 2021 Apr 12;11(3):907–928. doi: 10.1007/s13555-021-00519-7

Table 4.

Frequency of AD-related comorbidities among mild-to-moderate AD patients and matched non-AD controls in THIN

Comorbidities Mild-to-moderate AD
n (%)
Matched non-AD control
n (%)
Asthma 3757 (11.13%) 1801 (5.34%)
Smoking 2260 (6.70%) 2774 (8.22%)
Skin infections 2218 (6.57%) 508 (1.51%)
Depression 1093 (3.24%) 582 (1.72%)
Anxiety 1044 (3.09%) 395 (1.17%)
Allergic rhinitis 612 (1.81%) 166 (0.49%)
Sleep disorder 467 (1.38%) 193 (0.57%)
Allergic contact dermatitis 356 (1.05%) 31 (0.09%)
Ischaemic heart disease 322 (0.95%) 177 (0.52%)
Obesity 129 (0.38%) 54 (0.16%)

AD patients were propensity score matched with up to three non-AD controls based on demographics including age, sex, socio-economic status and practice ID

AD atopic dermatitis, THIN The Health Improvement Network