Table 5.

HCRU in mild-to-moderate AD patients compared with matched non-AD controls

Variable	Mean (SD) number per patient [Low 95% CI – High 95% CI]
	Mild-to-moderate AD patients	Matched non-AD control patientsb	p-value
GP visits	5.57 (0.04) [5.49–5.66]	3.59 (0.04) [3.50–3.67]	< 0.0001
Total referrals	0.97 (0.02) [0.94–1.00]	0.82 (0.02) [0.79–0.85]	< 0.0001
Mean non-AD related dermatology referralsa	0.03 (0.00) [0.029–0.036]	0.01 (0.00) [0.003–0.010]	< 0.0001
AD-related prescriptions	5.85 (0.05) [5.74–5.95]	0.68 (0.05) [0.580–0.786]	< 0.0001

AD atopic dermatitis, CI confidence Intervals, GP general practitioner, HCRU healthcare resource utilisation, SD standard deviations, THIN The Health Improvement Network

^aReferrals to an outpatient clinic or hospital

^bAD patients were propensity score matched with up to three non-AD controls based on demographics including age, sex, socio-economic status and practice ID