Fig. 5.

The gross morphology and Micro-computed tomography images of the samples at 8 and 12 weeks of post-surgery (A1-F1) Digital photographs of the samples (A2-F2) 2-dimensional projection images of the defects (A3-F3) and (A4-F4) show the transverse view and sagittal view of 3-dimensional (3D) reconstruction images, respectively (A5-F5) Images of new bone in the upper part of the defects. In 3D reconstruction images, off-white, green, and red indicate primary bone, new bone, and scaffolds, respectively. As compared with control group and bioactive glass ceramic (BGC) groups, Cu-BGC group displayed a considerable amount of neo-bone tissue in the defect region at 12 weeks.