Table 2.
Biomarkers in Convalescent and Chronic Takotsubo syndrome Stages.
| Chronic biomarkers in Takotsubo Syndrome | ||||||||
|---|---|---|---|---|---|---|---|---|
| Author | Year | No patients | Biomarker (units) | Timing of sample and cut-off | Takotsubo syndrome | Age and gender matched controls | P-Value | Reference range |
| Troponin I | ||||||||
| Scally et al. [2] | 2019 | 106 | (ng/L) | hsTroponin Ia at 5 months | 6.47 ± 0.6* | NA | NA | <5 (detectable limit) |
| Interleukin-6 | ||||||||
| Scally et al. [2] | 2019 | 106 | (pg/ml) | IL-6b at 5 months | 18.3 ± 5.17 | 6.5 ± 5.83 | 0.008 | NA |
| Interleukin-8 | ||||||||
| Scally et al. [2] | 2019 | 106 | (pg/ml) | IL-8c at 5 months | 61.9 ± 10.28 | 21.7 ± 10.86 | 0.009 | NA |
| BNPd | ||||||||
| Scally et al. [2] | 2019 | 106 | (pg/ml) | BNP at 5 months | 77.9 ± 45 (Mean ± SD) | 32.7 ± 4.6 | 0.003 | NA |
a
hsTroponin I- high sensitivity Troponin I.
b
IL-6- Interleukin-6.
c
IL-8- Interleukin-8.
d
BNP- Brain natriuretic peptide.
*
Value represented as mean ± standard deviation.