Table 1.
Characteristics of patients with fever for each period
| Characteristic | Control period (n = 5335) | Exposure period (n = 7423) | P-value |
|---|---|---|---|
| Age, years | |||
| Median (IQR) | 8 (3–11) | 10 (4–33) | < 0.001 |
| Category, n (%) | < 0.001 | ||
| 0–14 | 3147 (59.0) | 4152 (55.9) | |
| 15–64 | 2112 (39.6) | 3089 (41.6) | |
| ≥ 65 | 76 (1.4) | 182 (2.5) | |
| Male sex, n (%) | 2765 (48.2) | 3839 (48.3) | 0.90 |
| Month, n (%) | < 0.001 | ||
| December | 523 (9.8) | 1683 (22.7) | |
| January | 1704 (31.9) | 2052 (27.6) | |
| February | 1243 (23.3) | 2062 (27.8) | |
| March | 900 (16.9) | 1057 (14.2) | |
| April | 968 (18.1) | 570 (7.7) | |
| Diagnosis, n (%) | |||
| Upper respiratory tract infection | 4555 (85.4) | 5875 (79.1) | < 0.001 |
| Influenza | 1916 (35.9) | 2119 (28.5) | < 0.001 |
| Streptococcal infection | 78 (1.5) | 161 (2.2) | < 0.001 |
| Tonsillitis | 191 (3.6) | 254 (3.4) | 0.63 |
| Sinusitis | 15 (0.3) | 34 (0.5) | 0.11 |
| COVID-19 | 0 (0.0) | 6 (0.1) | 0.038 |
| Pneumonia | 38 (0.7) | 61 (0.8) | 0.49 |
| Asthma | 48 (0.9) | 40 (0.5) | 0.021 |
| Otitis media | 72 (1.4) | 106 (1.4) | 0.71 |
| Urinary tract infection | 24 (0.4) | 67 (0.9) | < 0.001 |
| Gastroenteritis | 773 (14.5) | 1064 (14.3) | 0.22 |
| Other abdominal disease | 35 (0.7) | 82 (1.1) | < 0.001 |
| Other | 138 (2.6) | 427 (5.7) | < 0.001 |
| Comorbidities, n (%) | |||
| Hypertension | 28 (0.5) | 65 (0.9) | 0.019 |
| Diabetes mellitus | 21 (0.4) | 40 (0.5) | 0.24 |
| Hyperlipidemia | 10 (0.2) | 17 (0.2) | 0.61 |
| Gout | 3 (0.1) | 5 (0.1) | 0.80 |
| Chronic lung disease | 178 (3.3) | 230 (3.1) | 0.45 |
| Heart failure | 0 (0) | 5 (0.1) | 0.06 |
| Liver disease | 6 (0.1) | 14 (0.2) | 0.27 |
| Cerebral infarction | 8 (0.2) | 14 (0.2) | 0.60 |
| Cancer | 30 (0.6) | 59 (0.8) | 0.12 |
| Collagen disease | 5 (0.1) | 6 (0.1) | 0.27 |
| Dementia | 3 (0.1) | 7 (0.1) | 0.45 |
COVID-19 coronavirus disease; IQR interquartile range