Table 5. Biochemical analysis of sera obtained from mice killed on 56th day post-treatments.
Organ function | Control | Castration | Orlistat | Combination | Reference range |
---|---|---|---|---|---|
Liver | |||||
ALP (U/l) | 154 ± 29 | 149 ± 30 | 158 ± 37 | 144 ± 31 | 63–178 |
ALB (g/dl) | 2.2 ± 0.2 | 2.6 ± 0.3 | 2.3 ± 0.3 | 2.3 ± 0.3 | 3.0–4.0 |
ALT (U/l) | 127 ± 27 | 147 ± 47 | 170 ± 25 | 160 ± 50 | 27–78 |
AST (U/l) | 48 ± 1 | 61 ± 21 | 104 ± 30 | 136 ± 28 | 20–215 |
Kidney | |||||
BUN (mg/dl) | 32 ± 6 | 28 ± 5 | 30 ± 8 | 33 ± 8 | 18–45 |
CRE (mg/dl) | 0.3 ± 0.1 | 0.4 ± 0.2 | 0.2 ± 0.1 | 0.2 ± 0.1 | 0.3–0.5 |
Reference range of biochemical data was obtained from the Charles River Laboratories (Wilmington, MA, U.S.A.).