Table 3. Univariate and Multivariable Analysis of Log IgG Values.
| Characteristic | Univariate analysis | Multivariable analysis | ||
|---|---|---|---|---|
| β (95% CI) | P value | β (95% CI) | P value | |
| Age | −0.02 (−0.05 to 0.01) | .11 | −0.03 (−0.07 to 0.01) | .10 |
| Sex | ||||
| Women | NA | NA | NA | NA |
| Men | −0.22 (−1.10 to 0.64) | .60 | −0.11 (−1.00 to 0.79) | .80 |
| Treatment | ||||
| Biological therapy | NA | NA | NA | NA |
| Chemotherapy | −0.79 (−2.20 to 0.65) | .30 | −1.20 (−2.70 to 0.40) | .15 |
| Chemotherapy + biological therapy | −1.10 (−2.60 to 0.46) | .20 | −1.20 (−2.90 to 0.53) | .20 |
| Chemotherapy + immunotherapy | −2.6 (−4.2 to −1.0) | .003 | −3.5 (−5.6 to −1.5) | .001 |
| Immunotherapy | −0.2 (−1.7 to 1.3) | .80 | −0.54 (−2.5 to 1.4) | .60 |
| Immunotherapy + biological | −1.8 (−4.00 to 0.38) | .11 | −2.00 (−4.50 to 0.48) | .12 |
| Days post vaccination | −0.02 (−0.07 to 0.03) | .40 | −0.04 (−0.10 to 0.01) | .13 |
| Cancer type | ||||
| Brain | NA | NA | NA | NA |
| Breast | 0.06 (−1.70 to 1.80) | >.90 | −0.30 (−2.00 to 1.40) | .70 |
| GI | −0.52 (−2.10 to 1.10) | .50 | 0.06 (−1.60 to 1.70) | >.90 |
| GU | −0.35 (−2.40 to 1.70) | .70 | 0.24 (−2.10 to 2.60) | .80 |
| Lung | −0.42 (−2.10 to 1.20) | .60 | 0.63 (−1.30 to 2.60) | .50 |
| Othera | 1.40 (−0.47 to 3.20) | .15 | 1.10 (−0.93 to 3.10) | .30 |
Abbreviations: GI, gastrointestinal; GU, genitourinary; NA, not applicable.
a
Other cancer types included cervix uteri squamous cell carcinoma, desmoid type fibromatosis, melanoma, mucoepidermoid carcinoma, nasopharynx squamous cell carcinoma, nonmelanoma skin squamous cell carcinoma, osteosarcoma, thymoma, and thyroid anaplastic carcinoma.