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The physicochemical and absorption, distribution, metabolism and elimination (ADME) properties of AZD3965, predicted from MedChem Designer. The prediction was based on the chemical structure of AZD3965. % represents the chance AZD3965 will be a substrate for the transporter or metabolizing enzyme
| Name | AZD3965 |
|---|---|
| pKa | 9.95 |
| Log P | 1.78 |
| Human fup (%) | 6.22 |
| Rat fup (%) | 21.7 |
| Pgp substrate | Yes (58%) |
| CYP3A4 substrate | Yes (98%) |
| UGT2B7 substrate | Yes (100%) |
