TABLE 1.
Characteristics of study participants used for analyses
| Participant characteristics | Mucosal P2Y6 expression analysis | P2Y6 quantification analysis | Urinary ATP and ADP concentration analyses |
|
|---|---|---|---|---|
| ATP | ADP | |||
| n | 10a | 28 | 66 | 60 |
| Age, mean (range), y | 61 (46-82) | 69 (37-92) | 52 (21-93) | 54 (21-93) |
| Sex | ||||
| Female | 7 | 10 | 49 | 36 |
| Male | 3 | 18 | 17 | 24 |
| ICIQ-OAB characteristics | ||||
| Frequencyb, mean (SD) | 0.77 (±0.42) | 0.52 (±0.33) | 0.37 (±0.31) | 0.36 (±0.32) |
| Nocturiab, mean (SD) | 0.73 (±0.34) | 0.56 (±0.27) | 0.15 (±0.18) | 0.17 (±0.19) |
| Urgencyb, mean (SD) | 0.75 (±0.31) | 0.36 (±0.23) | 0.17 (±0.18) | 0.20 (±0.20) |
| Incontinenceb, mean (SD) | 0.74 (±0.31) | 0.18 (±0.20) | 0.09 (±0.17) | 0.10 (±0.18) |
| Total ICIQ-OAB symptom scoreb, mean (SD) | 0.74 (±0.28) | 0.39 (±0.16) | 0.18 (±0.13) | 0.19 (±0.14) |
Abbreviations: ADP, adenosine diphosphate; ATP, adenosine triphosphate; ICIQ-OAB, International Consultation on Incontinence Questionnaire – Overactive Bladder.
a
Participants diagnosed as having OAB (for further information see Figure 1).
b
Symptoms scores were range standardized on a 0 to 1 scale.