Fig. 7. Obesity promotes dermal adiposity, fibrosis, and loss of AMP expression in human skin.
(A) Representative Bodipy (green) and phalloidin (PHA) staining of human back skin sections from lean (BMI <23) and obese individuals (BMI >29). All individuals who participated in the study are white Caucasians (n = 3 to 6 per group). Scale bar, 1 mm. (B to E) qRT-PCR analysis of indicated genes (ratio to housekeeping gene HPRT) in lean or obese human skin (n = 4 to 5 per group). All error bars indicate mean ± SEM. **P < 0.01; n.s., nonspecific (unpaired Student’s t test).