TABLE 2.

Clinicopathological factors, TDLN metastasis, and survival: Uni‐ and multivariate analysis

n = 169	Univariate analysis			Multivariate analysis
	HR	P	95% CI	HR	P	95% CI
Recurrence‐free survival
TDLN metastasis
None	Ref			Ref
Present	4.32	<.001	2.09‐8.89	4.27	.003	1.62‐11.23
pStage
0/I	Ref			Ref
II	8.35	<.001	2.75‐25.40	2.84	.107	0.80‐10.12
III/IV	14.16	<.001	5.05‐39.76	2.67	.115	0.79‐9.05
pGrade
0/1a	Ref			Ref
1b/2/3	0.33	.005	0.16‐0.71	0.37	.017	0.17‐0.84
Overall survival
TDLN metastasis
None	Ref			Ref
Present	3.90	.001	1.71‐8.90	3.35	.021	1.20‐9.36
pStage
0/I	Ref			Ref
II	6.38	.002	2.03‐20.06	2.29	.304	0.47‐11.16
III/IV	9.39	<.001	3.29‐26.81	2.59	.212	0.58‐11.52
pGrade
0/1a	Ref			Ref
1b/2/3	0.24	.008	0.08‐0.69	0.31	.034	0.11‐0.92

Abbreviations: LN, lymph node; TDLN, LN around thoracic duct.