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. 2021 Mar 19;147(7):1937–1955. doi: 10.1007/s00432-021-03597-4

Table 5.

Prognostic significance of the expression of glypicans on the relapse-free survival of breast cancer patients stratified by progesterone receptor (PR) status

Genes PR Status Relapse free survival
Number of cases HR 95% CI P value
GPC1 Positive 589 1.41 (0.99–2.01) 0.054
Negative 549 1.6 ( 1.19–2.16) 0.0017
GPC2 Positive 489 1.1 (0.75–1.61) 0.63
Negative 372 0.98 (0.69–1.4) 0.92
GPC3 Positive 589 0.94 (0.66–1.33) 0.72
Negative 549 1 (0.75–1.34) 1
GPC4 Positive 589 1.11 (0.78–1.57) 0.55
Negative 549 1.05 (0.79–1.41) 0.74
GPC5 Positive 589 1.18 (0.83–1.66) 0.36
Negative 549 0.99 (0.74–1.32) 0.93
GPC6 Positive 489 1.19 (0.81–1.74) 0.37
Negative 372 1.29 (0.9–1.84) 0.16

Bold typing of P values indicates a significance level P < 0.05

HR Hazard ratio, CI confidence interval