Table 2.
Differences Between Demographic Characteristics of Non-AKD and AKD Groups in the Training Cohort
| Demographic Characteristics | Overall (n=185) | Non-AKD (n=58) | AKD (n=127) | p value |
|---|---|---|---|---|
| AKI staging | <0.001 | |||
| Stage 1 | 12 (6.5) | 10 (17.2) | 2 (1.6) | |
| Stage 2 | 29 (15.7) | 17 (29.3) | 12 (9.4) | |
| Stage 3 | 144 (77.8) | 31 (53.4) | 113 (89) | |
| Admission to ICU | 0.100 | |||
| NO | 48(25.9) | 10(17.2) | 38(29.9) | |
| YES | 137(74.1) | 48(82.8) | 89(70.1) | |
| Admission to Nephrology | 0.432 | |||
| NO | 145(78.4) | 48(82.8) | 89(70.1) | |
| YES | 40(21.6) | 10(17.2) | 38(29.9) | |
| Sex | 0.318 | |||
| Female | 72 (38.9) | 19 (32.8) | 53 (41.7) | |
| Male | 113 (61.1) | 39 (67.2) | 74 (58.3) | |
| Age (years) | 0.223 | |||
| <35 | 34 (18.4) | 16 (27.6) | 18 (14.2) | |
| 35–45 | 32 (17.3) | 7 (12.1) | 25 (19.7) | |
| 45–55 | 45 (24.3) | 14 (24.1) | 31 (24.4) | |
| 55–65 | 29 (15.7) | 9 (15.5) | 20 (15.7) | |
| ≥65 | 45 (24.3) | 12 (20.7) | 33 (26.0) | |
| Hypertension | 0.434 | |||
| No | 125 (67.6) | 42 (72.4) | 83 (65.4) | |
| Yes | 60 (32.4) | 16 (27.6) | 44 (34.6) | |
| Diabetes | 0.393 | |||
| No | 169 (91.4) | 55 (94.8) | 114 (89.8) | |
| Yes | 16 (8.6) | 3 (5.2) | 13 (10.2) | |
| Oliguria | 0.027 | |||
| No | 167 (90.3) | 57 (98.3) | 110 (86.6) | |
| Yes | 18 (9.7) | 1 (1.7) | 17 (13.4) | |
| Proteinuria | 0.287 | |||
| No | 115 (62.5) | 40 (69.0) | 75 (59.5) | |
| Yes | 69 (37.5) | 18 (31.0) | 51 (40.5) | |
| Peak creatinine, µmol/L | <0.001 | |||
| <223 | 36 (19.5) | 25 (43.1) | 11 (8.7) | |
| 223–347.8 | 35 (18.9) | 16 (27.6) | 19 (15.0) | |
| 347.8–536 | 39 (21.1) | 9 (15.5) | 30 (23.6) | |
| 536–810 | 37 (20.0) | 5 (8.6) | 32 (25.2) | |
| ≥810 | 38 (20.5) | 3 (5.2) | 35 (27.6) | |
| BUN, mmol/L | 0.001 | |||
| <10.6 | 46 (24.9) | 25 (43.1) | 21 (16.5) | |
| 10.6–15.7 | 47 (25.4) | 12 (20.7) | 35 (27.6) | |
| 15.7–24.6 | 40 (21.6) | 11 (19.0) | 29 (22.8) | |
| ≥24.6 | 52 (28.1) | 10 (17.2) | 42 (33.1) | |
| UA | 0.304 | |||
| Normal | 62 (33.5) | 23 (39.7) | 39 (30.7) | |
| High | 123 (66.5) | 35 (60.3) | 88 (69.3) | |
| Anemia | 0.003 | |||
| No | 103 (55.7) | 42 (72.4) | 61 (48.0) | |
| Yes | 82 (44.3) | 16 (27.6) | 66 (52.0) | |
| PLT,×109/L | 0.035 | |||
| >100 | 151 (81.6) | 53 (91.4) | 98 (77.2) | |
| ≤100 | 34 (18.4) | 5 (8.6) | 29 (22.8) | |
| WBC,×109/L | 0.531 | |||
| ≤10 | 107 (57.8) | 36 (62.1) | 71 (55.9) | |
| >10 | 78 (42.2) | 22 (37.9) | 56 (44.1) | |
| TP, g/L | 0.565 | |||
| ≥60 | 127 (68.6) | 42 (72.4) | 85 (66.9) | |
| <60 | 58 (31.4) | 16 (27.6) | 42 (33.1) | |
| ALB, g/L | 0.032 | |||
| ≥40 | 67 (36.2) | 28 (48.3) | 39 (30.7) | |
| <40 | 118 (63.8) | 30 (51.7) | 88 (69.3) | |
| TC, mmol/L | 0.645 | |||
| <5.18 | 161 (87.0) | 49 (84.5) | 112 (88.2) | |
| ≥5.18 | 24 (13.0) | 9 (15.5) | 15 (11.8) | |
| TG, mmol/L | 0.962 | |||
| <1.7 | 100 (54.1) | 32 (55.2) | 68 (53.5) | |
| ≥1.7 | 85 (45.9) | 26 (44.8) | 59 (46.5) | |
| HDL, mmol/L | 0.496 | |||
| >1.04 | 59 (31.9) | 21 (36.2) | 38 (29.9) | |
| ≤1.04 | 126 (68.1) | 37 (63.8) | 89 (70.1) | |
| LDL, mmol/L | 0.874 | |||
| <3.37 | 159 (85.9) | 49 (84.5) | 110 (86.6) | |
| ≥3.37 | 26 (14.1) | 9 (15.5) | 17 (13.4) | |
| CRRT treatment | <0.001 | |||
| NO | 125(67.6) | 51(87.9) | 74(58.3) | |
| YES | 60(32.4) | 7(12.1) | 53(41.7) |
Notes: Peak creatinine is defined as the highest value of serum creatinine during AKI, Data are expressed as absolute frequencies, n (%). p values comparing Non-AKD group and AKD group are from χ2 test.
Abbreviations: BUN, blood urea nitrogen; UA, uric acid; PLT, platelet count; WBC, white blood cell; TP, total protein; ALB, albumin; TC, total cholesterol; TG, triglycerides; HDL, high-density lipoprotein; LDL, low-density lipoprotein.