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. 2021 May 25;14:2171–2180. doi: 10.2147/RMHP.S290763

Table 4.

Univariate Analysis of Factors Associated with Localized Pain at the Epidural Insertion Site

Risk Factor Number of Patients (n) Incidence (%) P value
Sex Male 3560 8.7 0.16
Female 1523 9.9
Age <50 2068 11.3 <0.001
≥50 3015 7.5
BMI <25 3862 9 0.954
≥25 1221 9.1
ASA class 1 2633 10.1 0.007
2–4 2450 7.9
Diabetes mellitus Yes 164 6.1 0.18
No 4919 9.1
Previous CNB history Yes 306 13.1 0.017
No 4777 8.7
Lumbar intervertebral disk hernia Yes 54 25.9 <0.001
No 5029 8.9
Type of surgery Orthopedic 1043 11.3 0.002
Urologic 1883 9.6
General 1302 6.5
Anorectal 336 7.4
Gynecological 71 7
Thoracic 38 7.9
Vascular 365 11
Duration of surgery <60 2498 9.7 0.098
≥60 2585 8.4
Puncture level Lumbar 4090 9.9 <0.001
Thoracic 993 5.7
Technical difficulty (more attempts at >1 interspace) Yes 4592 7.7 <0.001
No 491 22
Satisfactory block Yes 4821 8.9 0.242
No 262 11.1
Combined general anesthesia Yes 618 6.1 0.007
No 4465 9.5
Traumatic bleeding Yes 65 15.4 0.073
No 5018 9.0
Accidental dural puncture Yes 24 9.3 <0.001
No 5059 8.3
Unintentional paresthesia Yes 160 16.9 <0.001
No 4923 8.8
Ropivacaine Yes 4817 8.8 0.016
No 266 13.2
Postoperative PCEA Yes 873 4.8 <0.001
No 4210 9.9

Abbreviations: ASA, American Society of Anesthesiologists; PCEA, patient-controlled epidural analgesia.