Table 1.
Control n = 16,837 | Ischemic stroke n = 890 | Hemorrhagic stroke n = 70 | ||||||
---|---|---|---|---|---|---|---|---|
n | % | n | % | p value | n | % | p value | |
ALDH2 rs671 | 0.6642 | 0.8104 | ||||||
GG | 8554 | 50.80 | 458 | 51.46 | 33 | 47.14 | ||
GA | 6832 | 40.58 | 363 | 40.79 | 31 | 44.29 | ||
AA | 1451 | 8.62 | 69 | 7.75 | 6 | 8.57 | ||
ADH1B rs1229984 | 0.3012 | 0.7299 | ||||||
TT | 9159 | 54.40 | 477 | 53.60 | 39 | 55.71 | ||
TC | 6568 | 39.01 | 364 | 40.90 | 25 | 35.71 | ||
CC | 1110 | 6.59 | 49 | 5.51 | 6 | 8.57 | ||
Sex | 0.0874 | 0.2084 | ||||||
Women | 8724 | 51.81 | 435 | 48.88 | 31 | 44.29 | ||
Men | 8113 | 48.19 | 455 | 51.12 | 39 | 55.71 | ||
Age (mean ± SD) | 48.33 ± 10.90 | 58.47 ± 8.17 | < 0.0001 | 50.54 ± 10.60 | 0.0897 | |||
Educational level | < 0.0001 | 0.1665 | ||||||
Elementary school | 902 | 5.36 | 115 | 12.92 | 6 | 8.57 | ||
Junior/senior high school | 6498 | 38.59 | 418 | 46.97 | 32 | 45.71 | ||
University and above | 9437 | 56.05 | 357 | 40.11 | 32 | 45.71 | ||
Smoking (ref: never) | 0.0051 | 0.2571 | ||||||
Nonsmoker | 12,732 | 75.62 | 664 | 74.61 | 47 | 67.14 | ||
Former smoker | 2124 | 12.62 | 141 | 15.84 | 12 | 17.14 | ||
Current smoker | 1981 | 11.77 | 85 | 9.55 | 11 | 15.71 | ||
Alcohol intake | 0.0819 | 0.0212 | ||||||
No | 15,119 | 89.80 | 783 | 87.98 | 57 | 81.43 | ||
Yes | 1718 | 10.20 | 107 | 12.02 | 13 | 18.57 | ||
Physical activity | < 0.0001 | 0.9507 | ||||||
No | 10,041 | 59.64 | 376 | 42.25 | 42 | 60.00 | ||
Yes | 6796 | 40.36 | 514 | 57.75 | 28 | 40.00 | ||
BMI, kg/m2 (mean ± SD) | 24.23 ± 3.63 | 24.82 ± 3.65 | < 0.0001 | 24.64 ± 4.08 | 0.3547 | |||
Diabetes | < 0.0001 | 0.0204 | ||||||
No | 14,767 | 87.71 | 569 | 63.93 | 55 | 78.57 | ||
Yes | 2070 | 12.29 | 321 | 36.07 | 15 | 21.43 | ||
Hypertension | < 0.0001 | 0.0189 | ||||||
No | 13,246 | 78.67 | 352 | 39.55 | 47 | 67.14 | ||
Yes | 3591 | 21.33 | 538 | 60.45 | 23 | 32.86 | ||
Hyperlipidemia | < 0.0001 | 0.0148 | ||||||
No | 12,076 | 71.72 | 326 | 36.63 | 41 | 58.57 | ||
Yes | 4761 | 28.28 | 564 | 63.37 | 29 | 41.43 |
SD standard deviation; BMI body mass index
Bold font indicates statistical significance from publication