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. 2021 May 29;19:227. doi: 10.1186/s12967-021-02904-4

Table 1.

Descriptive data of the participants

Control n = 16,837 Ischemic stroke n = 890 Hemorrhagic stroke n = 70
n % n % p value n % p value
ALDH2 rs671 0.6642 0.8104
 GG 8554 50.80 458 51.46 33 47.14
 GA 6832 40.58 363 40.79 31 44.29
 AA 1451 8.62 69 7.75 6 8.57
ADH1B rs1229984 0.3012 0.7299
 TT 9159 54.40 477 53.60 39 55.71
 TC 6568 39.01 364 40.90 25 35.71
 CC 1110 6.59 49 5.51 6 8.57
Sex 0.0874 0.2084
 Women 8724 51.81 435 48.88 31 44.29
 Men 8113 48.19 455 51.12 39 55.71
Age (mean  ±  SD) 48.33 ± 10.90 58.47 ± 8.17 < 0.0001 50.54 ± 10.60 0.0897
Educational level < 0.0001 0.1665
 Elementary school 902 5.36 115 12.92 6 8.57
 Junior/senior high school 6498 38.59 418 46.97 32 45.71
 University and above 9437 56.05 357 40.11 32 45.71
Smoking (ref: never) 0.0051 0.2571
 Nonsmoker 12,732 75.62 664 74.61 47 67.14
 Former smoker 2124 12.62 141 15.84 12 17.14
 Current smoker 1981 11.77 85 9.55 11 15.71
Alcohol intake 0.0819 0.0212
 No 15,119 89.80 783 87.98 57 81.43
 Yes 1718 10.20 107 12.02 13 18.57
Physical activity < 0.0001 0.9507
 No 10,041 59.64 376 42.25 42 60.00
 Yes 6796 40.36 514 57.75 28 40.00
BMI, kg/m2 (mean  ±  SD) 24.23 ± 3.63 24.82 ± 3.65 < 0.0001 24.64 ± 4.08 0.3547
Diabetes < 0.0001 0.0204
 No 14,767 87.71 569 63.93 55 78.57
 Yes 2070 12.29 321 36.07 15 21.43
Hypertension < 0.0001 0.0189
 No 13,246 78.67 352 39.55 47 67.14
 Yes 3591 21.33 538 60.45 23 32.86
Hyperlipidemia < 0.0001 0.0148
 No 12,076 71.72 326 36.63 41 58.57
 Yes 4761 28.28 564 63.37 29 41.43

SD standard deviation; BMI body mass index

Bold font indicates statistical significance from publication