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. 2021 May 29;19:227. doi: 10.1186/s12967-021-02904-4

Table 2.

Association of ischemic stroke with alcohol intake by rs1229984

rs1229984 (TT) rs1229984 (TC/CC)
OR 95% CI p value OR 95% CI p value
Alcohol intake (ref: no)
 Yes 1.16 0.83–1.62 0.3954 0.99 0.70–1.39 0.9334
rs671 (ref: GG)
 GA/AA 1.14 0.93–1.38 0.2065 0.84 0.68–1.03 0.0933
Sex (ref: women)
 Men 0.91 0.72–1.15 0.4151 1.20 0.93–1.54 0.1577
Age 1.08 1.06–1.09 < 0.0001 1.07 1.05–1.08 < 0.0001
Educational level (ref: elementary school)
 Junior/senior high school 1.18 0.86–1.62 0.3039 1.04 0.74–1.46 0.8190
 University and above 0.98 0.70–1.37 0.9192 0.83 0.58–1.19 0.3111
Smoking (ref: nonsmoker)
 Former smoker 0.78 0.57–1.07 0.1198 1.06 0.78–1.46 0.6970
 Current smoker 1.07 0.75–1.53 0.7148 0.86 0.58–1.27 0.4455
Physical activity (ref: no)
 Yes 0.97 0.79–1.19 0.7897 1.12 0.90–1.39 0.3182
BMI 1.00 0.97–1.03 0.9358 1.00 0.97–1.03 0.9962
Diabetes (ref: no)
 Yes 1.43 1.15–1.79 0.0016 1.53 1.20–1.94 0.0006
Hypertension (ref: no)
 Yes 2.58 2.06–3.24 < 0.0001 2.04 1.61–2.60 < 0.0001
Hyperlipidemia (ref: no)
 Yes 1.48 1.18–1.85 0.0008 1.79 1.40–2.28 < 0.0001

OR odds ratio; CI 95% confidence interval; BMI body mass index

Bold font indicates statistical significance from publication