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. 2021 May 29;21:640. doi: 10.1186/s12885-021-08384-5

Table 2.

Univariate and multivariate cox analyses to evaluate the prognostic factors for OS

Variable Univariate analyses Multivariate analyses
HR 95% CI P HR 95% CI P
Age < 0.001
 30–49 Reference Reference
 50–69 1.146 0.928–1.414 0.205 1.198 0.969–1.480 0.095
 ≥ 70 1.626 1.310–2.019 < 0.001 1.767 1.421–2.198 < 0.001
Race 0.060
 White Reference Reference
 Black 1.000 0.873–1.144 0.997 0.962 0.839–1.103 0.579
 Others 0.776 0.630–0.955 0.016 0.734 0.595–0.905 0.004
Sex 0.030
 Male Reference Reference
 Female 0.911 0.837–0.992 0.0311 0.887 0.8135–0.966 0.006
T stage < 0.001
 T0 Reference Reference
 T1 1.449 0.970–2.164 0.070 1.343 0.898–2.008 0.151
 T2 1.582 1.074–2.330 0.020 1.451 0.984–2.140 0.060
 T3 1.830 1.242–2.698 0.002 1.664 1.127–2.456 0.010
 T4 1.775 1.210–2.603 0.003 1.623 1.104–2.387 0.014
N stage < 0.001
 N0 Reference Reference
 N1 0.964 0.795–1.168 0.707 0.931 0.768–1.129 0.469
 N2 1.242 1.090–1.414 0.001 1.230 1.079–1.402 0.002
 N3 1.236 1.068–1.431 0.005 1.220 1.052–1.415 0.009
Marriage < 0.001
 Unmarried Reference Reference
 Married 0.862 0.792–0.938 < 0.001 0.851 0.780–0.928 < 0.001