Table 2.
Signal pathways involved in XRCC2 in glioma based on three datasets
| Pathways | CGGA RNA-seq | CGGA microarray | TCGA RNA-seq | ||||||
|---|---|---|---|---|---|---|---|---|---|
| NES | NOM P -value | FDR q-value | NES | NOM P -value | FDR q-value | NES | NOM P -value | FDR q-value | |
| Cell cycle | 1.950 | 0.000 | 0.123 | 1.983 | 0.004 | 0.021 | 2.239 | 0.000 | 0.001 |
| DNA replication | 1.715 | 0.029 | 0.146 | 1.966 | 0.000 | 0.017 | 2.048 | 0.000 | 0.005 |
| Homologous recombination | 1.572 | 0.046 | 0.178 | 2.046 | 0.000 | 0.015 | 2.024 | 0.002 | 0.004 |
| Mismatch repair | 1.715 | 0.008 | 0.159 | 1.797 | 0.015 | 0.105 | 2.076 | 0.000 | 0.004 |
NES normalized enrichment score, NOM nominal, FDR false discovery rate. Gene sets with NOM P-value < 0.05 and FDR q-value < 0.25 were considered as significantly enriched, NOM nominal, FDR false discovery rate.