Table 2.

Antibacterial activity of the safrole oil versus the safrole nanoemulgel and amoxicillin as a positive control

Name	Negative control	Amoxicillin 750 (mm)	Safrole oil (mm)	Safrole nanoemulgel (mm)
Enterococcus faecium (ATCC 700221)	Resistance (No effect)	40.0 ± 0.70	11.0 ± 0.72	19.0 ± 1.40
E. Coli (ATCC 25922)	Resistance (No effect)	33.0 ± 0.81	Resistance (No effect)	Resistance (No effect)
Klebsiella (ATCC 13883)	Resistance (No effect)	18.0 ± 1.41	Resistance (No effect)	Partial resistance (Inhibition but the zone was not clear)
Pseudomonas aeruginosa (ATCC 9027)	Resistance (No effect)	40.0 ± 0.70	12.5 ± 0.71	20 ± 1.10
S. aureus (ATCC 25923)	Resistance (No effect)	42.0 ± 0.70	Partial resistance (Inhibition but the zone was not clear)	13.0 ± 1.41
MRSA (Clinically strain)	Resistance (No effect)	26.0 ± 1.41	Partial resistance (Inhibition but the zone was not clear)	14.5 ± 1.21
Proteus vulgaris (ATCC 8427)	Resistance (No effect)	38.0 ± 2.80	11.5 ± 0.70	17 ± 0.5
Candida	Resistance (No effect)	Resistance (No effect)	17.0 ± 0.80	22.0 ± 1.70