2. Comparison 3. Combination system compared to saliva ejector for reduction in the level of contamination in aerosols.
Combination system compared to saliva ejector for reduction in the level of contamination in aerosols | ||||||
Population: people undergoing aerosol generating procedures Setting: closed dental operatory Intervention: combination system (Isolite) Comparison: saliva ejector | ||||||
Outcomes | Anticipated absolute effects* (95% CI) | Relative effect (95% CI) | Number of participants (studies) | Certainty of the evidence (GRADE) | Comments | |
Risk with saliva ejector | Risk with combination system | |||||
Rate of infection of dental staff or patients | Not reported | |||||
Reduction in volume of contaminated aerosols in the operative environment | Not reported | |||||
Reduction in level of contamination in aerosols during ultrasonic scaling |
The mean CFU level was 3.61 | MD 0.31 CFU lower (0.82 lower to 0.20 higher) | ‐ | 50 (1 RCT)a | ⊕⊝⊝⊝ VERY LOW 1 | Mean data given in Log10 and the same was used in the analysis. |
Reduction in contamination of aerosols after ultrasonic scaling |
The mean CFU level was 2.00 | MD 0.35 CFU lower (0.99 lower to 0.29 higher) | ‐ | 50 (1 RCT)a | ⊕⊝⊝⊝ VERY LOW 1 | |
*The risk in the intervention group (and its 95% CI) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). CFU: colony forming units; CI: confidence interval; MD: mean difference; RCT: randomized controlled trial | ||||||
GRADE Working Group grades of evidence High certainty: we are very confident that the true effect lies close to that of the estimate of the effect Moderate certainty: we are moderately confident in the effect estimate: The true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different Low certainty: our confidence in the effect estimate is limited: The true effect may be substantially different from the estimate of the effect Very low certainty: we have very little confidence in the effect estimate: The true effect is likely to be substantially different from the estimate of effect |
1. Downgraded 2 levels for imprecision due to small sample size reported in a single study and 1 level for unclear risk of selection and reporting bias