3. Comparison 4. Combination system compared to rubber dam + HVE for reduction in the level of contamination in aerosols.
| Combination system compared to rubber dam + HVE for reduction in the level of contamination in aerosols | ||||||
| Population: people undergoing aerosol generating procedures Setting: dental clinic Intervention: combination system Comparison: rubber dam + HVE | ||||||
| Outcomes | Anticipated absolute effects* (95% CI) | Relative effect (95% CI) | Number of sites (studies) | Certainty of the evidence (GRADE) | Comments | |
| Risk with rubber dam + HVE | Risk with combination system | |||||
| Rate of infection of dental staff or patients | Not reported | |||||
| Reduction in volume of contaminated aerosols in the operative environment | Not reported | |||||
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Reduction in level of contamination in aerosols during water spray using high speed handpiece |
The mean CFU level was 133.70 | MD 125.20 CFU lower (174.02 lower to 76.38 lower) | ‐ | 24 ('n of 1' design) (1 RCT)a | ⊕⊝⊝⊝ VERY LOW 1 | |
| *The risk in the intervention group (and its 95% CI) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). CFU: colony forming units; CI: confidence interval; MD: mean difference; RCT: randomized controlled trial | ||||||
| GRADE Working Group grades of evidence High certainty: we are very confident that the true effect lies close to that of the estimate of the effect Moderate certainty: we are moderately confident in the effect estimate: The true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different Low certainty: our confidence in the effect estimate is limited: The true effect may be substantially different from the estimate of the effect Very low certainty: we have very little confidence in the effect estimate: The true effect is likely to be substantially different from the estimate of effect | ||||||
1. Downgraded 2 levels for unclear risk of selection bias and high risk of other bias, and 2 levels for imprecision due to small sample size reported in a single study