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The plasma concentration (ng/ml) of luvadaxistat at the steady state.
| Week 2 (1–2h) | Week 7 (4–8 h) | Week 12 (4–8 h) | |
|---|---|---|---|
| 75 mg BID | |||
| Patients, n | 13 | 13 | 12 |
| Mean plasma concentration, ng/ml (SD) | 183.2 (147.4) | 59.8 (28.3) | 52.8 (21.5) |
| 300 mg BID | |||
| Patients, n | 25 | 22 | 24 |
| Mean plasma concentration, ng/ml (SD) | 1063 (632) | 312 (159) | 340 (294) |
BID, twice daily; SD, standard deviation.
