Table 3.
Group | Cluster size, voxels | MNI coordinates | Brain regions | ||
---|---|---|---|---|---|
X | Y | Z | |||
bvFTD | 558 | −50 | −82 | 18 | Left lateral occipital cortex extending into angular gyrus |
487 | −20 | −10 | −10 | Left amygdala extending into putamen and insular cortex | |
465 | 10 | 28 | 20 | Right paracingulate gyrus extending into anterior cingulate gyrus | |
225 | 38 | −8 | −4 | Right insular cortex extending into right putamen | |
146 | 52 | 42 | 4 | Right frontal pole | |
144 | 64 | −58 | −4 | Right middle temporal gyrus | |
110 | 58 | −70 | 4 | Right lateral occipital cortex, inferior division extending into middle temporal gyrus | |
104 | 22 | 58 | 12 | Right frontal pole | |
101 | 12 | −38 | 2 | Right posterior cingulate gyrus extending into right thalamus | |
AD | NS | – | – | – | – |
All t values reported ≥4.454.
Significant grey matter intensity reduction in each patient group combined with controls voxel‐wise at the threshold of p < 0.001 (uncorrected) with a cluster threshold of 100 contiguous voxels.
AD, Alzheimer’s disease; bvFTD, behavioural‐variant Frontotemporal Dementia; MNI, Montreal Neurological Institute; NS, No significant results.