Table 5.

Effect of randomized treatment assignment to vitamin D and BASELINE statin use on migraine frequency and severity among those with a history of migraine (N=1022).

Change in migraine frequency
	Decrease in frequency		No Change		Increase in frequency		p-value for trend
	N	%	N	%	N	%
Placebo + no statin use	227	68.0	69	20.7	38	11.4
Statin use only	117	69.2	34	20.1	18	10.7	0.99
Vitamin D only	238	70.4	72	21.3	28	8.3	0.22
Vitamin D + statin use	121	66.9	39	21.6	21	11.6	0.47
Change in migraine severity
	Decrease in severity		No Change		Increase in severity		p-value for trend
	N	%	N	%	N	%
Placebo + no statin use	215	64.4	93	27.8	26	7.8
Statin use only	112	66.3	45	26.6	12	7.1	0.76
Vitamin D only	216	63.9	101	29.9	21	6.2	0.96
Vitamin D + statin use	117	64.6	54	29.8	10	5.5	0.76