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. Author manuscript; available in PMC: 2022 Apr 1.
Published in final edited form as: Curr Opin Pharmacol. 2021 Feb 19;57:89–97. doi: 10.1016/j.coph.2021.01.002

Figure 2. Interaction between individual susceptibility, circadian rhythms, behavioral triggers and environmental factors can increase the risk for adverse cardiovascular events.

Figure 2.

In vulnerable individuals (e.g. people with atherosclerosis), a behavioral trigger (e.g. exercise) can interact with underlying circadian rhythms in resting CV variables (e.g. hemostatic system) and lead to an adverse CV event. This interaction can also be affected by environmental factors (e.g. exercising in extreme temperatures).