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. Author manuscript; available in PMC: 2022 Jul 5.
Published in final edited form as: Eur J Med Chem. 2021 Apr 4;219:113425. doi: 10.1016/j.ejmech.2021.113425

Table 2.

Evaluation of cell growth inhibition of the synthesized MDM2 degraders in RS4;11 leukemia cells

graphic file with name nihms-1690864-t0016.jpg
Cmp. No n IC50 (nM) a
18 1 61
19 2 39
20 3 446
21 4 731
a.

The cell growth inhibition (IC50) of the compounds were measured in RS4;11 leukemia cells by Alarma Blue assay.