Table 3.

Peripheral Vascular Disease Risk in Study Participants According to rs17367504 Genotypes

	rs17367504 (AA)			rs17367504 (AG+GG)
	OR	95% CI	p-value	OR	95% CI	p-value
T2D (ref: No)
Yes	1.75	(1.35–2.26)	<0.001	0.94	(0.56–1.58)	0.811
Sex (ref: Female)
Male	0.63	(0.48–0.84)	0.001	0.55	(0.33–0.90)	0.019
Age, yr (ref: 30 to 39)
40 to 49	1.61	(0.94–2.75)	0.081	3.32	(1.24–8.92)	0.017
50 to 59	2.96	(1.80–4.88)	<0.001	5.27	(2.00–13.93)	0.001
60 to 70	4.88	(2.93–8.14)	<0.001	5.73	(2.07–15.86)	0.001
Smoking (ref: No)
Yes	1.44	(1.05–1.98)	0.025	1.00	(0.54–1.86)	1.000
Alcohol drinking (ref: No)
Yes	0.93	(0.63–1.37)	0.710	1.94	(0.99–3.80)	0.054
Physical activity (ref: No)
Yes	1.28	(1.02–1.62)	0.037	1.01	(0.66–1.55)	0.956
BMI (ref:18.5≤BMI<24)
BMI<18.5	0.52	(0.16–1.65)	0.265	0.44	(0.06–3.34)	0.428
24≤BMI<27	0.97	(0.74–1.26)	0.792	1.02	(0.63–1.63)	0.952
BMI≥27	1.55	(1.16–2.06)	0.003	0.77	(0.43–1.37)	0.372
Hypertension (ref: No)
Yes	1.39	(1.08–1.79)	0.012	2.31	(1.44–3.72)	0.001
Hyperlipidemia (ref: No)
Yes	1.76	(1.36–2.28)	<0.001	1.50	(0.94–2.39)	0.093
Atrial fibrillation (ref: No)
Yes	0.77	(0.23–2.58)	0.666	1.49	(0.17–12.84)	0.716
Tea consumption (ref: No)
Yes	0.85	(0.67–1.09)	0.196	0.56	(0.35–0.91)	0.019
Coffee consumption (ref: No)
Yes	0.99	(0.77–1.26)	0.924	1.00	(0.64–1.57)	0.993
Diet Type (ref: Omnivore)
Lacto-ovo vegetarian	0.80	(0.29–2.23)	0.668	2.56	(0.86–7.63)	0.092
Strict vegetarian	0.60	(0.37–0.98)	0.040	0.90	(0.38–2.15)	0.818

Note: The p-value for the interaction between rs17367504*diabetes is 0.0076.

Abbreviations: T2D, type 2 diabetes; OR, odds ratio; CI, confidence interval; BMI, body mass index; AA and AG+GG, genotypes of rs17367504 polymorphism; yr, year.