Figure 3.

Margin Separation Score and Purulent Exudate Score

(A) Margin separation score of all wounds by study arm. Mean scores ± SD are shown for 0 to 28 days post-treatment. The number (n) of monitored wounds decreased after 14 days due to termination of the first cohort of animals for histological and drug content sampling at the study midpoint. The observed rate of wound closure trended consistently across all 3 study arms, with scores decreasing with increased healing. (B) Purulent exudate score of all wounds by study arm. Mean scores ± SD are shown for 0 to 28 days post-treatment. The number (n) of scored wounds decreased after 14 days due to termination of the first cohort of animals for histological and drug content sampling. Scores for all arms trended in a similar manner with exudate largely resolved after 2 weeks, although scores for high-dose arm (PCB × 3) were consistently less than the other 2 arms. Abbreviations as in Figure 1.