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. 2021 May 31;10:34. doi: 10.1186/s40164-021-00228-z

Table 3.

Blood parameters and coagulation factors of influenza patients are compared before and after treatment

Influenza Normal range Before treatment (n = 400) After treatment (n = 400) p value
Blood cell counts
White blood cells, × 109/L 3.5–9.5 7.3 (5.3–9.9) 6.5 (5.1–8.4)  < 0.0001
Neutrophils, × 109/L 1.8–6.3 5.4 (3.6–7.7) 4.8 (3.4–6.6)  < 0.0001
Lymphocytes, × 109/L 1.1–3.2 1.1 (0.8–1.5) 1.3 (0.9–1.8) 0.014
Monocytes, × 109/L 0.1–0.6 0.5 (0.4–0.8) 0.5 (0.4–0.7) 0.002
Red blood cells, × 1012/L 4.3–5.8 4.2 (3.7–4.6) 4.2 (3.7–4.6) 0.212
Hemoglobin, g/L 130–175 127.0 (112.0–137.8) 126.0 (109.0–139.0) 0.988
Hematocrit, % 40–50 37.9 (33.9–41.7) 37.7 (32.8–41.0) 0.257
Platelet, × 109/L 125–350 203.5 (152.3–267.0) 216.0 (166.0–275.5)  < 0.0001
Mean platelet volume, fL 7.4–12.5 10.7 (9.8–11.6) 10.6 (10.0–11.6) 0.405
Coagulation panel
Prothrombin time, s 9–13 12.2 (11.4–14.1) 11.6 (10.9–12.4) 0.560
INR 0.8–1.2 1.0 (1.0–1.2) 1.1 (1.0–1.2) 0.645
aPTT, s 23.3–32.5 27.4 (24.7–31.3) 27.3 (24.9–29.7) 0.027
Thrombin time, s 14–21 17.7 (16.7–19.5) 17.5 (16.4–19.0)  < 0.0001
Fibrinogen, g/L 2–4 4.2 (3.2–5.3) 3.5 (2.8–4.1)  < 0.0001
D-dimer, mg/L  < 0.55 1.1 (0.5–2.5) 0.6 (0.4–1.2)  < 0.0001