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. 2021 May 17;8:672000. doi: 10.3389/fmed.2021.672000

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Copyright © 2021 Cai, Zhu, Lu, Zhu, Liu, Zhan, Ni, Gu, Zhang and Mou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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AAC ≤ 4, relationship between soluble Klotho level and CVD mortality in MHD patients. For patients with no or mild calcification (AAC ≤ 4), the high level of soluble Klotho level (sKl > 567.8 ng/L) patients had a lower risk of CVD death than in those with low level of soluble Klotho level (sKl ≤ 567.8 ng/L). Kaplan-Meier analysis with log-rank test revealed a significant difference between groups (P = 0.004).