TABLE 1.
Main characteristics of the women with a normal pregnancy (n = 64) enrolled for the study.
| 1st trimester | 2nd trimester | 3rd trimester | p value | |
|---|---|---|---|---|
| Nugent score | ||||
| 0–3 (normal microbiota) | 50% (32/64) | 73.4% (47/64) | 79.7% (51/64) | 0.0008 |
| 4–6 (intermediate microbiota) | 37.5% (24/64) | 15.6% (10/64) | 14.1% (9/64) | |
| 7–10 (bacterial vaginosis) | 12.5% (8/64) | 11% (7/64) | 6.2% (4/64) | |
| Gestational age (weeks; mean ± SD) | 10.4 ± 1.3 | 22.6 ± 0.8 | 32.5 ± 0.7 | — |
| Vaginal Candida spp. | 15.6% (10/64) | 15.6% (10/64) | 15.6% (10/64) | 1.0 |
| -C. albicans | 6/10 | 6/10 | 8/10 | |
| -C. glabrata | 3/10 | 3/10 | 1/10 | |
| -C. krusei | 1/10 | 1/10 | 1/10 | |
| Vaginal WBC count | ||||
| <5 (minimal or no inflammation) | 76.5% (49/64) | 78.1% (50/64) | 73.4% (47/64) | 0.8 |
| ≥5 (significant inflammation) | 23.4% (15/64) | 21.9% (14/64) | 26.5% (17/64) | |