Table 2.
Top 10 hub gene of B cells, T cells and monocytes present in RA and SLE.
| Cell types | Diseases | Top 10 hub genes |
|---|---|---|
| CD19+ B cells | RA | BPTF, MRPS28, SF1, PSAP, HNRNPC, ICT1, PHC2, JARID2, DICER1, ERBB2 |
| SLE | OAS1, XAF1, RSAD2, MX1, STAT1, OASL, IFIT3, OAS3, OAS2, IFIH1 | |
| CD4+ T cells | RA | STAT5B, SOCS3, JUN, STAT1, KRAS, PTEN, FGFR2, DICER1, ALB, CD44 |
| SLE | CENPE, MELK, NCAPG, AURKA, BUB1, TOP2A, CCNB1, KIF23, PBK, KIF11 | |
| CD14+ Monocytes | RA | RPL15, SOCS3, SIRT1, SERBP1, SKP2, TUBA1A, IMP3, EXOSC5, SMAD4, KRAS |
| SLE | IFIT1, ISG15, MX1, OAS2, OASL, IFIT2, IFIT3, OAS1, RSAD2, OAS3 |