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. 2021 May 17;12:669814. doi: 10.3389/fphar.2021.669814

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Copyright © 2021 Tan, Wang, Liu, Shi, Zhou, Zhou, Yang, Chen and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Forest plots for each outcome. (A) Pooled analysis in change in HbA1c. (B) Pooled analysis in PBS. (C) Pooled analysis in FPG. (D) Pooled analysis in any adverse event. (E) Pooled analysis in severe adverse event. (F) Pooled analysis in adverse effect leading to discontinuation. (G) Pooled analysis in any gastrointestinal adverse event. (H) Pooled analysis in vomiting. (I) Pooled analysis in diarrhea. (J) Pooled analysis of flatulence. (K) Pooled analysis of nausea. (L) Pooled analysis of abdominal pain. (M) Pooled analysis of any cause of death. Abbreviations: HbA1c, hemoglobin A1C; PBS, postprandial blood glucose; FPG, fasting plasma glucose.